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Biology · University

Allele frequency from diploid genotype counts

Count copies of the allele, not just individuals carrying it. No equilibrium assumption is needed.

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Method and conditions

Count copies of the allele, not just individuals carrying it. No equilibrium assumption is needed.

pA = (2NAA + NAa)/(2Ntotal)

Worked examples

A diploid population sample contains 34 AA, 15 Aa, and 32 aa individuals. Find the frequency of allele A. Round the final result to 4 decimal places if needed.

There are 83 A copies among 162 total copies.

0.5123

A diploid population sample contains 26 AA, 41 Aa, and 17 aa individuals. Find the frequency of allele A. Round the final result to 4 decimal places if needed.

There are 93 A copies among 168 total copies.

0.5536

Try it

  1. A diploid population sample contains 52 AA, 40 Aa, and 3 aa individuals. Find the frequency of allele A. Round the final result to 4 decimal places if needed.

  2. A diploid population sample contains 4 AA, 27 Aa, and 57 aa individuals. Find the frequency of allele A. Round the final result to 4 decimal places if needed.

Check your work

Answers and marking notes
  1. 0.7579

    There are 144 A copies among 190 total copies.

  2. 0.1989

    There are 35 A copies among 176 total copies.

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